Stroke Prevention Strategies: Annual Risk of Ischemic Stroke
Based on CHADS2 SCORE and Treatment Regimen
|
Chad Score |
0 |
1 |
2 |
3 |
4 |
5 |
6 |
|
No Therapy (Annual risk of ischemic stroke Annual risk of major bleed: 0.6% |
1.9%
|
2.8%
|
4.0% |
5.9% |
8.5% |
12.5% |
18.2% |
|
Aspirin Annual risk of major bleed: 1.1% |
1.5% |
2.2%
|
3.1% |
4.6% |
6.6% |
9.8% |
14.2% |
|
Warfarin Annual risk of major bleed: 2.4-2.8% |
0.6%
|
0.9% |
1.3% |
1.9% |
2.8% |
4.1% |
6.0% |
|
ASA + Clopidogrel Annual risk of major bleed: 2-2.2% |
1.1%
|
1.6% |
2.2% |
3.3% |
4.8% |
7.0% |
10.2% |
CHADS2 SCORE (add up score and determine risk per table above)
1 point = CHF/LV dysfunction, diagnosed at any time in the past
1 point = Hypertension – controlled or uncontrolled
1 point = Age > 75
1 point = Diabetes, Type I or II, controlled or uncontrolled
2 points = TIA or stroke at any time in the past
References: JAMA 2001;285:2
Peter Loewen Pharm.D. (peter.loewen@vch.ca)