|
Table of Contents
PARENTERAL AGENTS FOR THE MANAGEMENT OF HYPERTENSIVE CRISES
| Drug |
Dose |
Onset (minutes) |
Peak Effect |
Duration |
| alpha & beta blocker |
Labetalol
(Trandate®) |
20-80mg IV q10 mins prn |
5-10 |
5-15 mins |
3-6 hrs |
| beta blocker |
|
|
|
|
Propranolol
(Inderal®) |
1-3mg IV q4-6h prn |
2-5 |
15 mins |
3-6 hrs |
Metoprolol (Lopressor®,
Betaloc®) |
5-15mg IV q6h prn |
2-5 |
20 mins |
5-8 hrs |
Esmolol
(Brevibloc®) |
500mcg/kg load, then 50-200 mcg/kg/min |
1-2 |
|
10-30 mins |
| Vasodilator |
| Hydralazine (Apresoline®) |
10-20mg IV q1-4h prn |
5-20 |
10-80 mins |
2-6 hrs |
| Nitroprusside (Nipride®) |
0.3-10 mcg/kg/min |
0.5 |
2-3 mins |
Nitroglycerin
(Tridil®) |
5-100 mcg/min OR
0.2-1.5 mcg/kg/min |
2-5 |
5-10mins |
| ACE Inhibitor |
Enalaprilat1
(Vasotec® IV) |
1.25mg IV q6h prn |
15 |
1-4 hrs |
4-6 hrs |
| alpha
blocker |
| Phentolamine (Rogitine®) |
5-15mg IV, repeat prn |
1-2 |
2-4 mins |
3-10 mins |
1 non formulary drug
|