Table of Contents

 

  Stroke Prevention Strategies: Annual Risk of Ischemic Stroke
  Based on CHADS2 SCORE and Treatment Regimen

 

Chad Score

0

1

2

3

4

5

6

No Therapy

(Annual risk of ischemic stroke
with no therapy)

               Annual risk of

  major bleed: 0.6%

1.9%

 

 

 

2.8%

 

 

 

4.0%

5.9%

8.5%

12.5%

18.2%

Aspirin

               Annual risk of

  major bleed: 1.1%

1.5%

2.2%

 

3.1%

4.6%

6.6%

9.8%

14.2%

Warfarin

               Annual risk of

        major bleed: 2.4-2.8%

0.6%

 

0.9%

1.3%

1.9%

2.8%

4.1%

6.0%

ASA + Clopidogrel

               Annual risk of

    major bleed: 2-2.2%

1.1%

 

1.6%

2.2%

3.3%

4.8%

7.0%

10.2%

 

   CHADS2 SCORE (add up score and determine risk per table above)

   1 point = CHF/LV dysfunction, diagnosed at any time in the past

   1 point = Hypertension controlled or uncontrolled

   1 point = Age > 75

   1 point = Diabetes, Type I or II, controlled or uncontrolled

   2 points = TIA or stroke at any time in the past

 

   References: JAMA 2001;285:2
                    
Peter Loewen Pharm.D. (peter.loewen@vch.ca)