Table of Contents


Oral midazolam is administered as a pre-anesthetic agent for pediatric patients. The usual dose is 0.5-0.75mg/kg.1 The dose is drawn up from the ampoule and mixed with juice prior to administration due to its bitter taste. The bioavailability of oral midazolam is 15-27%, onset of action 10-20 minutes, and duration of sedation 20 minutes to 3 hours.2

1Feld LH et al. Anesthesiology 1990;73:831-4.
Betcher DL et al. J Ped Onc Nurs 1992;9:136-8.

(adapted from VHHSC newsletter volume 1, number 1, September 1994)