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Table of Contents
PROPERTIES OF BETA-BLOCKERS
|
Drug |
B-1
Selective |
ISA |
Lipid
Solubility |
Dose
Equivalence |
Major
Route of Elimination |
Once
Daily Dosing |
|
Acebutolol1 |
Yes |
1+ |
Low-Mod |
200mg |
Hepatic,
Renal |
Yes |
|
Atenolol1 |
Yes |
-- |
Low |
50mg |
Renal |
Yes |
|
Bisoprolol1
|
Yes |
-- |
Mod |
10mg |
Hepatic |
Yes |
|
Carvedilol |
No |
-- |
Mod |
50mg |
Hepatic |
No
|
|
Esmolol1
|
Yes |
-- |
Low |
|
Blood
Esterases |
No |
|
Labetalol1 |
No |
-- |
Mod |
200mg |
Hepatic |
No |
|
Metoprolol1
|
Yes |
-- |
Mod |
100mg |
Hepatic |
Yes (SR
prep'n) |
|
Nadolol1 |
No |
-- |
Low |
80mg |
Renal |
Yes |
|
Oxprenolol |
No |
2+ |
Mod |
80mg |
Hepatic |
No |
|
Pindolol
|
No |
3+ |
Mod |
7.5mg |
Hepatic,
Renal |
Yes |
|
Propranolol1
|
No |
-- |
High |
80mg |
Hepatic |
Yes (LA
prep'n) |
|
Sotalol1 |
No |
-- |
Low |
80mg |
Renal |
No |
|
Timolol |
No |
-- |
Low |
10mg |
Hepatic |
No |
1
formulary drug; ISA = Instrinsic Sympathomimetic Activity |