Table of Contents

COMPARISON OF ANGIOTENSIN II RECEPTOR BLOCKERS (ARBs)

 

Drug

 

 

Dose Equivalence

 

Maximum Daily Dose

candesartan (ATACAND)1

 

8 to 16 mg3

32 mg

eprosartan (TEVETON)2

 

600 mg

800 mg

irbesartan (AVAPRO)2

 

150 mg

300 mg

losartan (COZAAR)1

 

50 mg

100 mg

olmesartan (OLMETEC)2

20 mg

40 mg

telmisartan (MICARDIS)2

 

40 mg

80 mg

valsartan (DIOVAN)1

 

80 mg

160 mg
(160 mg BID evaluated in heart failure studies)

1formulary drug
2automaticaly interchanged to candesartan at an equivalent dose given once daily

3Conversion TO Candesartan (per Regional Therapeutic Interchange)
eprosartan 600 mg, irbesartan 150 mg, losartan 50 mg, olmesartan 20 mg, telmisartan 40 mg,
valsartan 80 mg
are equivalent to candesartan 8 mg

Conversion FROM Candesartan
Use clinical judgement; consider more conservative conversion to avoid hypotension
i
.e. candesartan 16 mg is equivalent to eprosartan 600 mg, irbesartan 150 mg, losartan 50 mg,
olmesartan 20 mg, telmisartan 40 mg, valsartan 80 mg