Table of Contents

5-ASA PRODUCTS AVAILABLE IN CANADA

Brand Name (Manufacturer)
Dosage Form
(Active Ingredient)
Site Uses Dosage
Asacol®1
(Procter and Gamble)
400mg SR tab
Enteric-coated
pH>7 release
(Mesalamine)
Colon UC,
CD of colon
400-800mg TID
Salofalk®1
(Axcan)
250, 500mg
Enteric-coated
pH>6 release
Supps, enemas
(Mesalamine)
Ileum (30%),
Colon
UC,
CD of colon & ileum
500mg - 1g TID-QID
Mesasal®
(Glaxo Smith Kline)
250, 500mg tab
Enteric-coated
pH>6 release
(Mesalamine)

Ileum (30%),
Colon

UC,
CD of colon & ileum

500mg - 1g TID
Pentasa®1
 
(Ferring)
250mg SR tab
Ethylcellulose coated microspheres
(Mesalamine)
Duodenum,
Jejunum,
Ileum,
Colon
UC,
CD of D, J, ileum & colon
500mg - 1g QID
Dipentum®
(Pharmacia)
250mg caps
(Olsalazine - 2 x 5-ASA molecules cleaved by bacteria)
Colon UC
CD of colon ?
500mg QID (taper up)

1 formulary drug

UC = ulcerative colitis; CD = Crohn's disease; D = duodenum; J = jejunum