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Table of Contents
5-ASA PRODUCTS AVAILABLE IN CANADA
| Brand Name
(Manufacturer) |
Dosage Form
(Active
Ingredient)
|
Site |
Uses |
Dosage |
Asacol®1
(Procter and Gamble) |
400mg SR tab
Enteric-coated
pH>7 release
(Mesalamine)
|
Colon |
UC,
CD of colon |
400-800mg TID |
Salofalk®1
(Axcan) |
250, 500mg
Enteric-coated
pH>6 release
Supps, enemas
(Mesalamine)
|
Ileum (30%),
Colon |
UC,
CD of colon & ileum |
500mg - 1g TID-QID |
Mesasal®
(Glaxo Smith Kline) |
250,
500mg tab
Enteric-coated
pH>6 release
(Mesalamine)
|
Ileum
(30%),
Colon
|
UC,
CD of colon & ileum
|
500mg - 1g TID |
Pentasa®1
(Ferring) |
250mg SR tab
Ethylcellulose coated
microspheres
(Mesalamine)
|
Duodenum,
Jejunum,
Ileum,
Colon |
UC,
CD of D, J, ileum & colon |
500mg - 1g QID |
Dipentum®
(Pharmacia) |
250mg caps
(Olsalazine - 2 x 5-ASA molecules cleaved by bacteria) |
Colon |
UC
CD of colon ? |
500mg QID (taper up) |
1 formulary drug
UC = ulcerative colitis; CD = Crohn's disease; D = duodenum; J
= jejunum
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