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(C) Vancouver
General Hospital.
This monograph may not be reproduced without permission.
For further information, please contact a Pharmacist. |
NAME OF DRUG
codeine phosphate
CLASSIFICATION
Narcotic Analgesic
ALTERNATE NAME
methylmorphine phosphate
INDICATIONS
- symptomatic treatment of mild to moderate pain
- control of exhausting, non-productive cough when oral antitussives are not feasible
RECONSTITUTION AND STABILITY
- stable at room temperature
COMPATIBILITY
- incompatible with most drugs
- see Appendix X for syringe compatibilities
ROUTES OF ADMINISTRATION
VH & HSC ADMINISTRATION POLICY
DOSAGE
Analgesic:
Usual - Adult:
- 30 mg SC, IM every 4 hours
- range: 15-60 mg SC, IM every 4 hours
Children: 0.5-1 mg/kg/dose SC or IM in 4-6 divided doses
Maximum:
- 6-12 years 60 mg/day
- 2-6 years 30 mg/day
Antitussive:
- Adults: 10-20 mg SC, IM every 4-6 hours
See Appendix XI for equianalgesic narcotic dosages
POTENTIAL HAZARDS OF PARENTERAL ADMINISTRATION
- convulsions (in children particularly), respiratory depression, hypotension,
cyanosis, coma with large doses
- NOT RECOMMENDED for IV administration because of increased possibility of histamine
reactions
IMPORTANT IMPLICATIONS
- constipation, nausea, vomiting, dizziness, drowsiness are most common side effects
- use with caution in patients with respiratory depression, coma, seizures, shock,
asthma, COPD, and hepatic dysfunction
Rev. April 1994